Case definition and management of patients with MERS coronavirus in Saudi Arabia

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MERS Coronavirus in Dromedary Camel Herd, Saudi Arabia

A prospective study of a dromedary camel herd during the 2013-14 calving season showed Middle East respiratory syndrome coronavirus infection of calves and adults. Virus was isolated from the nose and feces but more frequently from the nose. Preexisting neutralizing antibody did not appear to protect against infection.

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Exposures among MERS Case-Patients, Saudi Arabia, January–February 2016

References 1. Platt L, Easterbrook P, Gower E, McDonald B, Sabin K, McGowan C, et al. Prevalence and burden of HCV co-infection in people living with HIV: a global systematic review and meta-analysis. Lancet Infect Dis. 2016;16:797–808. http://dx.doi.org/10.1016/S1473-3099(15)00485-5 2. Joint United Nations Programme on HIV/AIDS. Malawi: HIV and AIDS estimates (2015). [cited 2016 Jul 7]. http:/...

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Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia.

Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir. Our surveillance in Saudi Arabia in 2014 and 2015 showed that viruses of the MERS-CoV species and a human CoV 229E-related lineage co-circulated at high prevalence, with frequent co-infections in the upper respiratory tract of dromedary c...

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Human Infection with MERS Coronavirus after Exposure to Infected Camels, Saudi Arabia, 2013

We investigated a case of human infection with Middle East respiratory syndrome coronavirus (MERS-CoV) after exposure to infected camels. Analysis of the whole human-derived virus and 15% of the camel-derived virus sequence yielded nucleotide polymorphism signatures suggestive of cross-species transmission. Camels may act as a direct source of human MERS-CoV infection.

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We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.

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ژورنال

عنوان ژورنال: The Lancet Infectious Diseases

سال: 2014

ISSN: 1473-3099

DOI: 10.1016/s1473-3099(14)70918-1